What is the purpose of combining long-acting and short-acting nicotine replacement therapies?

The purpose of combining long-acting and short-acting nicotine replacement therapies is primarily to enhance the chance of quitting by effectively managing cravings throughout the day. Long-acting nicotine replacement therapies, such as patches, provide a steady level of nicotine to help alleviate withdrawal symptoms over an extended period. However, they may not be sufficient alone to address acute cravings that can occur at specific times, particularly when a person is exposed to triggers or stressors associated with smoking.

Short-acting nicotine replacement therapies, such as gum or lozenges, can be used on an as-needed basis to address these sudden cravings quickly. By utilizing both types of therapies, individuals can maintain a stable level of nicotine while also having the ability to "top up" when immediate cravings arise, thereby significantly increasing their chances of successfully quitting smoking. This combination approach targets both the physiological dependence on nicotine and the behavioral aspects of smoking cessation, making it a comprehensive strategy for aiding individuals in their quitting journey.