Which approach is most likely to assist in long-term cessation success?

Combining multiple interventions is recognized as the most effective approach to achieving long-term smoking cessation success. This strategy involves integrating pharmacotherapy with behavioral therapy and support systems, which addresses both the physical dependence on nicotine and the psychological aspects of addiction.

Research consistently supports that using a combination of medications—such as nicotine replacement therapy, bupropion, or varenicline—alongside behavioral therapies can significantly increase the chances of quitting successfully. The individual is not only managing withdrawal symptoms through medication but also developing coping strategies and support networks that can help maintain cessation in the long run.

In contrast, relying solely on cold turkey methods can make the cessation process more challenging due to withdrawal symptoms and cravings, which are often difficult to manage without additional support. Similarly, using just a single medication may not address the complexities of addiction as thoroughly as a multi-faceted approach can. Avoiding behavioral therapy altogether misses the opportunity for important psychological support and coping strategies, which can be crucial for maintaining long-term quit success. Thus, combining multiple interventions is the superior approach for sustaining smoking cessation efforts.